IDC_Tamai et al_Identification of circadian clock modulators from existing drugs

The dataset was generated from a cell-based, high-throughput chemical screen. Triplicate wells of human U2OS cells were treated with compounds from the International Drug Collection at a concentration of 1 uM or 10 uM. Substances contained in all the wells, including blanks, are listed in the Excel file along with the effect of the drug/DMSO control on circadian period. The change in circadian period compared to the DMSO control is plotted in the graphs. Drugs that killed the cells were not included in the final figure of the paper. Another file containing the screening of FDA-approved compounds has been uploaded separately.