Crystal structure of MKK7 (MAP2K7) covalently bound with CPT1-70-1
收藏Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of MKK7 (MAP2K7) covalently bound with CPT1-70-1 Descriptor: 1,2-ETHANEDIOL, Dual specificity mitogen-activated protein kinase kinase 7, N-(4-((2-((4-(4-methylpiperazin-1-yl)phenyl)amino)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy)phenyl)acrylamide Authors: Chaikuad, A, Tan, L, Wang, J, Liang, Y, Gray, N.S, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2020-03-27 Release date: 2020-08-12 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Catalytic Domain Plasticity of MKK7 Reveals Structural Mechanisms of Allosteric Activation and Diverse Targeting Opportunities. Cell Chem Biol, 27, 2020
创建时间：
2020-03-27
