Trancriptomic profiling of liver tumors in rats after chronical phenobarbital treatment

Here we investigate the difference in global gene expression in different tumor types found in the liver of rats after NNM-initiation/PB-promotion of tumor growth. We aim to identify tumor characteristic expression in nodules, focii, adenomas and carcinomas.本研究旨在探究经N-甲基亚硝基脲（N-Nitrosomethylurea, NNM）启动肿瘤生长、苯巴比妥（Phenobarbital, PB）促癌后，大鼠肝脏内发现的不同肿瘤类型的全局基因表达差异，并识别结节、病灶、腺瘤与癌的肿瘤特征性表达模式。