AntigenDB: an immunoinformatics database of pathogen antigens

Welcome to the official repository for AntigenDB, a comprehensive and manually curated database of experimentally validated antigens from pathogenic organisms. This resource is designed to support researchers in vaccine development, immunoinformatics, computational vaccinology, and microbiology. Web Server: https://webs.iiitd.edu.in/raghava/antigendb/ Citation Ansari, H. R., Flower, D. R., & Raghava, G. P. S. (2010). AntigenDB: an immunoinformatics database of pathogen antigens. Nucleic Acids Research, 38 (Database issue), D847–D853. https://doi.org/10.1093/nar/gkp830 About the Database AntigenDB is a specialized, value-added database of experimentally validated antigens derived from pathogenic organisms. Unlike existing epitope-oriented databases (IEDB, MHCBN, AntiJen, BCIPEP), AntigenDB is antigen-centric — it covers all experimentally determined antigens regardless of whether epitope information is known, including the large class of protective antigens for which no epitope has yet been identified. The database integrates information from: Literature (PubMed, ScienceDirect) Public repositories (SwissProt, GenBank, PDB, GEO, IEDB, MHCBN, AntiJen, BCIPEP) Specialized databases (dbPTM, PhosphoELM, RESID, InterPro, DBSubLoc, PSORTdb, IMGT, SYFPEITHI) Key Features Massive Dataset Over 500 antigen entries (proteins, glycoproteins, and lipoproteins) Derived from 44 important pathogenic species Crystal structure data available for 290 out of 504 antigens