首页/数据集/TDP-43 can directly affect splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways

TDP-43 can directly affect splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways

ChEBI2015-08-11 更新2026-07-12 收录

RNA剪接调控

神经退行性机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-67195 数据链接链接失效反馈

官方服务：

资源简介：

TDP-43 can directly affect splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways

应用场景：

创建时间：

2015-08-11

神经退行性机制

胶质细胞功能研究

GRN haploinsufficiency causes frontotemporal lobar degeneration and results in microglial hyperactivation, lysosomal dysfunction and TDP-43 deposition. To understand the contribution of microglial hyp

NIAID Data Ecosystem30

The lysine demethylase KDM7A regulates immediate early genes in neurons [CUT&Tag]

神经元表观遗传调控

神经退行性机制

There are multiple post-translational modifications on amino acid residues at the N-terminus of histones that affect the structure of chromatin and alter the transcription of genes, thereby regulating

NIAID Data Ecosystem00

DNA damage burden causes selective CUX2 neuron loss in neuroinflammation

神经退行性机制

神经元DNA修复机制

Neurodegeneration shows regional and cell-type-specific patterns in ageing and disease1, but the underlying mechanisms for cell type-specific neuronal losses remain poorly understood. Previous studies

NIAID Data Ecosystem00

Table_2_Progressive mitochondrial dysfunction in cerebellar synaptosomes of cystatin B-deficient mice.XLSX

神经退行性机制

线粒体生物能量学

The involvement of mitochondrial dysfunction in cystatin B (CSTB) deficiency has been suggested, but its role in the onset of neurodegeneration, myoclonus, and ataxia in the CSTB-deficient mouse model

NIAID Data Ecosystem10

Enhanced sensitivity of hippocampal pyramidal neurons from mdx mice to hypoxia-induced loss of synaptic transmission.

神经退行性机制

神经元缺氧复氧损伤

The gene at the Duchenne/Becker muscular dystrophy locus encodes dystrophin, a member of a protein superfamily that links the actin cytoskeleton to transmembrane plasmalemmal proteins. In mature skele

PubMed Central1992-03-15 更新00

TDP-43 can directly affect splicing profiles and isoform production of genes involved in the apoptotic and mitotic cellular pathways

资源简介：

相关数据集