Metabolic enzymes’ projected maximal regulatory trap-space equal to 0 in RASF-specific initial conditions and their associated catalyzed reaction constrained to 0 in MitoCore.
Flux rates of Colombos conditions. Full list of Colombos conditions and the corresponding flux rates predicted using trilevel linear programming. (XLSX 364 kb)
Code for the examples A.rar file with the MATLAB files code to perform the examples described below with Example of flux estimation under data scarcity (a), P. pastoris (b) and E. coli (c). (RAR 5 kb)
Performing oxidative phosphorylation is the primary role of respiratory chain both in bacteria and eukaryotes. Yet, the branched respiratory chains of prokaryotes contain alternative, low energy-coupl