Enrolment characteristics and gametocyte carriage in relation to mutations in the dhfr gene.

AUC = area under the curve; GM = geometric mean; IQR = interquartile range; Non-ACT = treatment with sulphadoxine-pyrimethamine (SP) alone or in combination with amodiaquine; ACT = treatment with SP and artesunate (3 days).¥Gametocyte densities were measured by Pfs25 QT-NASBA.*Mutations were determined at enrolment: double mutation = mutations in c108+c59 or c108+c51; three mutations = mutations in c51+c59+c108;¶the period from enrolment until time of feeding (day 14) was considered for determining the AUC.