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Transcriptional profiling of intestinal changes following APC loss

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NIAID Data Ecosystem2026-04-30 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP136270
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资源简介:
Vil-CreERT2 was used to drive loss of APC (Adenomatous polyposis coli) in the murine intestinal epithelium. 4 days post induction, mice were sampled and 1cm of tissue from the proximal intestine was collected into RNA later. This was compared to control (wild-type) intestine. This analysis allows investigation of transcriptional changes following APC loss (and therefore activation of the WNT signalling pathway). Overall design: RNAseq Expression data from whole intestine comparing WT intestine vs VilCreER APCfl/fl
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2022-11-23
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