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NS1-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections; insights into 1918 H1N1 pandemic

ChEBI2014-11-03 更新2026-07-21 收录

流感病毒致病性

急性肺损伤与细菌共感染

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-62169 数据链接链接失效反馈

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NS1-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections; insights into 1918 H1N1 pandemic

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创建时间：

2014-11-03

流感病毒致病性

H5N1病毒进化

Low pathogenicity avian influenza (LPAI) viruses of the H7 subtype generally cause mild disease in poultry. However the evolution of a LPAI virus into highly pathogenic avian influenza (HPAI) virus re

NIAID Data Ecosystem50

A single N342D substitution in Influenza B Virus NA protein determines viral pathogenicity in mice

流感病毒致病性

分子标记

Influenza B virus (IBV) is one of the most important human respiratory viruses: it causes approximately one-third of the global influenza-related disease burden each year. However, compared with the s

NIAID Data Ecosystem20

RNA-seq data of 293T cells trasfected with different viral PA-X proteins of influenza viruses

流感病毒致病性

病毒-宿主相互作用

PA-X is a small accessory protein that modulates the virulence of various influenza A virus both in mammals and birds. However, the specific role of PA-X in the pathogenesis of highly pathogenic avian

NIAID Data Ecosystem10

Table_2_C57BL/6J and C57BL/6NJ Mice Are Differentially Susceptible to Inflammation-Associated Disease Caused by Influenza A Virus.XLSX

流感病毒致病性

宿主遗传易感性

Influenza viruses cause seasonal epidemics and sporadic pandemics, and are a major burden on human health. To develop better countermeasures and improve influenza disease outcomes, a clearer understan

NIAID Data Ecosystem50

The 1918 PB2 protein, not HA, enhances the virulence of an avian influenza virus closely related to the 1918 pandemic virus through the inhibition of wnt signaling.

流感病毒致病性

Wnt信号通路调控

The purpose of this experiment was to understand the pathogenic role of individual 1918 genes on the host response to the 1918 pandemic influenza virus. We examined reassortant avian viruses nearly i

NIAID Data Ecosystem20

NS1-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections; insights into 1918 H1N1 pandemic

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