Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme.
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Allosteric peptidic inhibitor of human thymidylate synthase that stabilizes inactive conformation of the enzyme. Descriptor: CG peptide, SULFATE ION, Thymidylate synthase Authors: Tochowicz, A, Finer-Moore, J, Stroud, R.M, Costi, M.P. Deposit date: 2012-06-04 Release date: 2013-03-06 Last modified: 2024-11-27 Method: X-RAY DIFFRACTION (2 Å) Cite: Alanine mutants of the interface residues of human thymidylate synthase decode key features of the binding mode of allosteric anticancer peptides. J.Med.Chem., 58, 2015
创建时间:
2012-06-04



