EDN1

ENCODES a protein that exhibits endothelin A receptor binding (ortholog); endothelin B receptor binding (ortholog); INVOLVED IN adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway (ortholog); artery smooth muscle contraction (ortholog); blood vessel morphogenesis (ortholog); PARTICIPATES IN endothelin signaling pathway; hypoxia inducible factor pathway; inflammatory response pathway; ASSOCIATED WITH acute kidney failure (ortholog); Acute Lung Injury (ortholog); adult respiratory distress syndrome (ortholog); FOUND IN basal part of cell (ortholog); extracellular space (ortholog); rough endoplasmic reticulum lumen (ortholog); INTERACTS WITH 6-oxoprostaglandin F1alpha; ambrisentan; carvedilol

编码一种蛋白，该蛋白具备内皮素A受体结合（同源）；内皮素B受体结合（同源）；参与腺苷酸环化酶抑制型G蛋白偶联受体信号通路（同源）；动脉平滑肌收缩（同源）；血管形态发生（同源）；参与内皮素信号通路；缺氧诱导因子途径；炎症反应途径；与急性肾衰竭（同源）；急性肺损伤（同源）；成人呼吸窘迫综合征（同源）；位于细胞基底部（同源）；细胞外空间（同源）；粗面内质网腔（同源）；与6-氧代前列腺素F1alpha；阿马布司坦；卡维地洛相互作用。