Stability and biocompatibility of a Bionic Eye - Ophthalmoscopy, intraocular pressure, optical coherence tomography and radiography data

Data related to: Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep

In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7) breeds were implanted in the left eye with a suprachoroidal retinal stimulator (Bionic Eye) for durations up to 100 days. The surgical safety, implant stability and device biocompatibility were assessed.

All procedures were performed conducted in accordance with the Australian Code for the Care and Use of Animals for Experimental Purposes 8th edition (2013) and the ARVO standards for use of animals in ophthalmic research and approved by the Animal Care and Ethics Committee (ACEC) of UNSW Sydney (protocol number 14/155B) .

Animal identifier:
Animals were identified according to the experimental group to which they were assigned (duration of experiment 2 days, 1 month, 2 months and 3 months.
E.g.: 2D#1 was the first animal in the group implanted for a duration of 2 Days. 3M#3 was the third animal in the group implanted for 3 Months.

Fundus and infrared imaging:
Indirect ophthalmoscopy and infrared images were acquired as video files from which still frames were extracted using VLC Media Player software (Free Software Foundation, Inc., Boston, USA).

Intraocular pressure:
A TonoVet rebound tonometer (Icare Oy, Helsinki, Finland) was used to measure the intraocular pressure at different times before and after implantation of the Bionic Eye.

Optical Coherence Tomography:
OCT imaging was performed with an Envisu 2300 system (BiOptigen, Morrisvile NC, USA) and images acquired in the group implanted for a duration of 3 months.

本研究数据集涉及一项关于新型98通道脉络膜视网膜植入式视觉假体的植入及其长期稳定性与生物相容性评估。在Eggenberger等人研究中，选取了来自萨福克（N=2）和道珀（N=7）品种的九只绵羊，在左侧眼植入该假体，植入期限最长可达100天。本研究对手术安全性、植入稳定性和设备生物相容性进行了评估。

所有实验操作均遵循2013年发布的《澳大利亚用于实验目的的动物护理与使用准则》第8版以及ARVO关于眼科研究中动物使用的标准，并经新南威尔士大学悉尼（UNSW Sydney）动物护理与伦理委员会（ACEC）批准（协议编号14/155B）。

动物标识：
动物根据分配的实验组别进行标识（实验期限分别为2天、1个月、2个月和3个月。例如：2D#1代表在2天实验期限中植入的第一只动物；3M#3代表在3个月实验期限中植入的第三只动物。

眼底及红外成像：
通过间接眼底镜和红外成像技术获取视频文件，并使用VLC媒体播放器软件（Free Software Foundation, Inc., Boston, USA）从中提取静态帧。

眼内压：
使用TonoVet反弹式眼压计（Icare Oy, Helsinki, Finland）在不同时间点测量植入Bionic Eye前后眼内压。

光学相干断层扫描（OCT）：
使用Envisu 2300系统（BiOptigen, Morrisvile NC, USA）进行OCT成像，并收集植入期限为3个月的实验组图像。