BoNT/A1, BoNT/A2, and BoNT/A3 protection by the murine and chimeric TA12 mAbs.
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MAb protection activity was determined using the mouse protection assay with 5 estimated MLD50/ml of BoNT/A1, BoNT/A2 or BoNT/A3 and serial dilutions of mAbs. 5 estimated MLD50/mouse were incubated for 30 min at room temperature with 2,500 to 0.25 ng of Mab and the mixture (0.5 ml) was injected intraperitoneally in each mouse of a group of 8 to 10 mice. Results are expressed as the number of surviving mice versus the total number of mice. ND, not done.
创建时间:
2015-12-02



