Functional characterization of novel GLI2 mutations identified in patients with Combined Pituitary Hormone Deficiency
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In a preliminary experiment, the GLI2ΔN-WT induced up to 10-fold reporter activity 306 (p<0.0001) compared with GLI2FL-WT (Supplementary figure 1) due to the absence of the 307 repressor domain, in line with the previous reports.<br><br>Primers used for the amplification of the complete coding region of GLI2.<br>
提供机构：
Małgorzata Wasniewska
创建时间：
2018-07-12
