Histone H4 and CXCL10 expression after S. pyogenes infection.
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(A) Histone H4 was immunostained by Western blot analysis in the supernatants from air pouch of C57BL/6 wild-type mice inoculated with S. pyogenes (AP1 strain) for 4h, 8h, and 24h. p33 treatment was administrated 8h after infection. Note that the shift in the molecular weight of histone H4 recovered from the air pouch compared to recombinant histone H4 is due to histone acetylation and/or methylation [28]. (B) CXCL10 was measured by ELISA in the supernatant from air pouch of C57BL/6 wild-type mice inoculated with S. pyogenes (AP1 strain, n = 3), infected mice treated with p33 8h after infection (n = 3), and mice injected with p33 only (n = 3).
创建时间：
2016-02-23
