首页/数据集/BET inhibition releases the Mediator complex from specific cis elements in acute myeloid leukemia cells (RNA-Seq I)

BET inhibition releases the Mediator complex from specific cis elements in acute myeloid leukemia cells (RNA-Seq I)

NIAID Data Ecosystem2026-03-11 收录

急性髓系白血病分子特征

转录调控与表观遗传学

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE74650 数据链接链接失效反馈

官方服务：

资源简介：

Genome occupancy profiling by high throughput sequencing PolyA selected RNA-seq for shRNA-expressing MLL-AF9 transformed acute myeloid leukemia cells (RN2)

应用场景：

创建时间：

2019-05-15

急性髓系白血病分子特征

蛋白质质谱分析

Additional file 7. Table S2. Mass spectrometry data

Figshare2024-02-07 更新50

Identification and interrogation of the gene regulatory network of CEBPA double mutant Acute Myeloid Leukaemia [KO52 ATAC-seq]. Identification and interrogation of the gene regulatory network of CEBPA double mutant Acute Myeloid Leukaemia [KO52 ATAC-seq]

急性髓系白血病分子特征

基因调控网络

Acute myeloid leukaemia (AML) is a heterogeneous haematological malignancy caused by mutations in genes encoding transcriptional and epigenetic regulators together with signalling genes. It is charact

NIAID Data Ecosystem20

Global Identification of the miR-130a targetome in human HSPC Reveals a Novel Role for TBL1XR1 in Hematopoietic Stem Cell Self-Renewal and t(8;21) AML

造血干细胞调控

急性髓系白血病分子特征

Gene expression profiling and proteome analysis of normal and malignant hematopoietic stem cells (HSC) point to shared core stemness properties. However, discordance between mRNA and protein signature

NIAID Data Ecosystem10

Gene expression changes in THP1 AML cells following Withaferin A exposure. Gene expression changes in THP1 AML cells following Withaferin A exposure

急性髓系白血病分子特征

药物基因调控

Connectivity map analysis using an AML-specific cMYB gene signature (Walf-Vorderwulbecke et al. Leukemia. 2018;32(4):882-889. 10.1038/leu.2017.317) identified withaferin A (WFA) as a candidate cMYB de

NIAID Data Ecosystem20

CITE-seq (cellular indexing of transcriptomes and epitopes by sequencing) of WT and RAS mutant specimens from acute myeloid leukemia (AML) patients.. CITE-seq (cellular indexing of transcriptomes and epitopes by sequencing) of WT and RAS mutant specimens from acute myeloid leukemia (AML) patients.

急性髓系白血病分子特征

RAS基因突变

To understand the role of RAS mutations in AML, we performed CITE-seq on diagnosis specimens from WT and RAS mutant AML patients. Overall design: Cells were harvested from AML patients at diagnosis an

NIAID Data Ecosystem10

BET inhibition releases the Mediator complex from specific cis elements in acute myeloid leukemia cells (RNA-Seq I)

资源简介：

相关数据集