Gene expression changes in fetuses exposed to ethanol in utero. Mus musculus

Timed pregnant C57Bl6 mice were exposed to ethanol during a critical period, gestational day 15 to 18, of cerebral cortical development to identify gene expression changes in the cerebral cortex of developing fetus due to this ethanol exposure Keywords: Compared animals exposed to ethanol (alcohol fed group) to a pair-fed control group and both groups were normalized to a control group (animals fed adlibitum) Overall design: We analyzed 14, dual labeled, 22K Mouse arrays where one channel (Ch1) represents the sample for animals fed with alcohol (alcohol fed group) or to animals fed with maltose dextrose (pair-fed group) and the other channel (Ch2) corresponds to universal control (total RNA from 7 animals fed adlibitum with food and water; control)