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Expression profiling of laser-microdissected tissue from APPPS1 plaque-depositing mouse model of Alzheimer's disease

ChEBI2014-11-04 更新2026-07-21 收录

阿尔茨海默病分子机制

小鼠基因表达分析

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-15058 数据链接链接失效反馈

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资源简介：

Expression profiling of laser-microdissected tissue from APPPS1 plaque-depositing mouse model of Alzheimer's disease

应用场景：

创建时间：

2014-11-04

阿尔茨海默病分子机制

单细胞转录组学

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that mostly strikes the elderly. However, the exact molecular and cellular pathogenesis of AD, especially the dynamic changes of ne

NIAID Data Ecosystem90

REST and Neural Gene Network Dysregulation in iPS Cell Models of Alzheimer’s Disease (RNA-seq data set)

阿尔茨海默病分子机制

iPSC神经分化

Alzheimer’s disease (AD) is preceded by a long prodromal period of decades during which pathology accumulates in the brain prior to the onset of dementia. The molecular basis of these changes as well

NIAID Data Ecosystem40

AD vs Control, Human Frontal Lobe, Synaptosome.

阿尔茨海默病分子机制

RNA定位

Proper transport of RNAs to synapses is essential for localized translation of proteins in response to synaptic signals and synaptic plasticity. Alzheimer’s disease (AD) is a neurodegenerative disease

NIAID Data Ecosystem20

Additional file 7: of Identification of the novel activity-driven interaction between synaptotagmin 1 and presenilin 1 links calcium, synapse, and amyloid beta

阿尔茨海默病分子机制

突触蛋白相互作用

Supporting data values. The file presents individual values recorded in the experiments where nâ<â6. (XLSX 270 kb)

NIAID Data Ecosystem80

Combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau

磷酸化tau蛋白

阿尔茨海默病分子机制

Abnormal changes in the neuronal microtubule-associated protein Tau, such as high phosphorylation and aggregation, are considered hallmarks of cognitive deficits in Alzheimer disease. Abnormal phospho

NIAID Data Ecosystem30

Expression profiling of laser-microdissected tissue from APPPS1 plaque-depositing mouse model of Alzheimer's disease

资源简介：

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