Commensal Staphylococcal species that can cause acute urinary tract infections. Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305 = NCTC 7292

Staphylococcus saprophyticus subsp. saprophyticus ATCC 15305. This strain (GTC 265; ATCC 15305) is the type strain for the species and the sequenced strain was obtained from the Japanese Society for Bacteriology (Tokyo). The original ATCC isolate was from a human urine specimen. It will be used for comparative genomics with other Staphylococcal genomes. Genomic analysis revealed that this organism does not encode many of the virulence factors found in S. aureus. It does contain a capsular polysaccharide biosynthetic locus and a genomic island encoding antibiotic resistance determinants. Virulence factors include adhesins that mediate adherence to urinary tract epithelial cells, a number of paralogous transport system, and a putative iron-uptake system as well as the aforementioned antiobiotic and polysaccharide loci.