Vitamin D receptor ChIP-Seq in primary prostate epithelial cells
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https://www.ncbi.nlm.nih.gov/sra/SRP175036
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资源简介：
We investigated the genomic activity of vitamin D in primary prostate epithelial cells (PrE) through vitamin D receptor (VDR)-ChIP-sequencing. PrE cells treated with 50 nM 1,25D showed nuclear localization the VDR within 1 hr, persisting until 4 hr, and a 2 hr treatment was selected for ChIP-seq. Rigorous testing of the ChIP conditions and VDR antibody were performed. Nearly 5,000 VDR binding sites were identified. Overall design: One primary prostate epithelial cell line treated with ethanol (control) or 50 nM 1,25-VitaminD3 for 2 hr
创建时间：
2021-01-20
