Multiplexed functional assessment of dominant genetic variants in CARD11
收藏NIAID Data Ecosystem2026-03-12 收录
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资源简介：
We describe the use of saturation genome editing to measure the effects of CARD11 variants on protein function, splicing and lymphoma cell survival. We find the results to predict the clinical effects of the variants. Overall design: Saturation genome editing of the N-terminal 145 amino acids in CARD11.
创建时间：
2021-03-01
