Tear Cytokines in Retinitis Pigmentosa

Retinitis pigmentosa (RP) is the most common inherited retinal dystrophy and has been linked to mood and sleep disturbances. Tear fluid is a convenient, non-invasive biofluid for biomarker research, as its composition varies with health status and reflects ocular neuroimmune pathways. In this observational case-control study, a large cohort of RP patients was analyzed for a custom panel of cytokines, chemokines, growth factors, and substance P.