Association of high-sensitivity cardiac troponin T with mortality and cardiovascular events in a community-based prospective study in Beijing

Objective: The prognostic value of cardiac troponins in apparently healthy populations is not well established. The aim of this study was to investigate the prognostic properties of high-sensitivity cardiac troponin T (hs-cTnT) for long-term adverse outcomes.
Setting: A community-dwelling prospective survey of residents from two communities in Beijing.
Participants: From September 2007 to January 2009, 1680 participants were initially enrolled. Of these, 1499 (870 females, mean age: 61.4 years) participants completed the survey and were followed up for a median of 4.8 years (interquartile range: 4.5–5.2).
Outcome measures: The primary outcome was the occurrence of all-cause mortality and major cardiovascular events.
Results: Overall, 820 individuals (54.7%) had detectable hs-cTnT levels. During the follow-up, 52 participants (3.5%) died, 154 (10.3%) had major cardiovascular events, and 99 (6.6%) experienced new-onset coronary events. Compared with those with undetectable hs-cTnT lev...