Identification of factors associated with high fat diet induced insulin resistance

Whole genome expression profilling were undertaken in high fat diet (HFD)-fed obese rats to identify the genetic factors associated with metabolic dysfunction, insulin resistance and obesity.本研究以高脂饮食（HFD）喂养的肥胖大鼠为研究对象开展全基因组表达谱分析，旨在筛选与代谢功能紊乱、胰岛素抵抗及肥胖相关的遗传因素。