Crystal structure of human Arginase-1 complexed with inhibitor 9
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Crystal structure of human Arginase-1 complexed with inhibitor 9 Descriptor: Arginase-1, MANGANESE (II) ION, [(5R)-5-amino-5-carboxy-7-(piperidin-1-yl)heptyl](trihydroxy)borate(1-) Authors: Cousido-Siah, A, Mitschler, A, Ruiz, F.X, Whitehouse, D.L, Golebiowski, A, Ji, M, Zhang, M, Beckett, P, Sheeler, R, Andreoli, M, Conway, B, Mahboubi, K, Schroeter, H, Van Zandt, M.C, Podjarny, A. Deposit date: 2012-11-09 Release date: 2013-03-20 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (1.298 Å) Cite: Discovery of (R)-2-Amino-6-borono-2-(2-(piperidin-1-yl)ethyl)hexanoic Acid and Congeners As Highly Potent Inhibitors of Human Arginases I and II for Treatment of Myocardial Reperfusion Injury. J.Med.Chem., 56, 2013
创建时间：
2012-11-09
