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Trypanosoma brucei PTR1 (TbPTR1) in complex with pyrimethamine

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Protein Data Bank Japan2024-01-31 更新2026-03-28 收录
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Trypanosoma brucei PTR1 (TbPTR1) in complex with pyrimethamine Descriptor: 5-(4-CHLORO-PHENYL)-6-ETHYL-PYRIMIDINE-2,4-DIAMINE, ACETATE ION, GLYCEROL, ... Authors: Tassone, G, Landi, G, Pozzi, C, Mangani, S. Deposit date: 2021-05-31 Release date: 2021-07-14 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (1.34 Å) Cite: Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase. Pharmaceuticals, 14, 2021
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2021-05-31
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