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Effect of NS1 alanine substitutions on DENV reporter virus replication.

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https://figshare.com/articles/dataset/_Effect_of_NS1_alanine_substitutions_on_DENV_reporter_virus_replication_/1601762
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The replication level of a given mutant relative to the wild-type (WT) is displayed. Replication was determined by measuring luciferase activity 48 h post-transfection and normalizing to the 4 h value that reflects transfection efficiency. Values represent mean ± standard deviation of three independent experiments. NS1 mutants with severe defects in viral RNA replication are underlined, while asterisks (*) indicate mutants with selective defects in virus assembly or release. Effect of NS1 alanine substitutions on DENV reporter virus replication.
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2015-11-12
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