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Yeast RNA polymerase III elongation complex
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2024-11-20
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Pausing of RNA polymerase II regulates mammalian developmental potential
The remarkable capacity for pluripotency and self-renewal in embryonic stem cells (ESCs) requires a finely-tuned transcriptional circuitry wherein the genes and pathways that initiate differentiation
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Additional file 6 of Functional genomic profiling of O-GlcNAc reveals its context-specific interplay with RNA polymerase II
Additional file 6: Table S5. List of omics datasets.
DataCite Commons2025-03-25 更新60
Tyrosine phosphorylation of RNA Polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells. Homo sapiens
In mammals, the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II consists of 52 conserved heptapeptide repeats containing the consensus sequence Tyr1-Ser2-Pro3-Thr4-Ser5-Pro6-Ser7. Post-transl
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RNA polymerase II phosphorylated on CTD serine 5 interacts with the spliceosome during co-transcriptional splicing. Nojima et al: MOLECULAR-CELL-D-17-01996R2:
The highly intronic nature of protein coding genes in mammals necessitates a co-transcriptional splicing mechanism as revealed by mNET-seq analysis. Immuno-precipitation of MNase digested chromatin wi
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BMH-21 inhibits RNA polymerase I transcription cycle and rDNA occupancy
The objective of this study was to determine the effect of a small-molecule Pol I inhibitor, BMH-21, on rRNA synthesis in vivo. NET-seq was performed to determine the Pol I occupancy after BMH-21 trea
NIAID Data Ecosystem40
