FOXO1 is an oncogenic mediator in AML1-ETO leukemia
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https://www.ncbi.nlm.nih.gov/sra/SRP074342
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资源简介：
Transcriptome analysis by RNAseq of human CD34+ hematopoietic stem and progenitor cells transduced with empty vector control(MIT), AML1-ETO (AE), wildtype FOXO1 (F WT) or FOXO1 DNA binding deficient mutant (F DB). We find wildtype FOXO1 partially recapitulates gene signature of AML1-ETO Overall design: Human CD34+ hematopoietic stem and progenitor cells from three donors were transduced with retrovirus expressing MIT, AE, F WT or F DB. Transduced cells were sorted at day 5 after transduction, RNA was collected for RNAseq.
创建时间：
2017-12-17
