Senescent cells and the incidence of age-related diseases

NIAID Data Ecosystem2026-03-12 收录

细胞衰老机制

年龄相关疾病

数据链接：

https://data.mendeley.com/datasets/hg6m5p78yy 数据链接链接失效反馈

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资源简介：

Supplementary data files for the MS "Senescent cells and the incidence of age-related diseases"

创建时间：

2020-11-04

Premature Senescence and Increased TGFβ Signaling in the Absence of Tgif1

细胞衰老机制

TGF-β信号通路

Transforming growth factor β (TGFβ) signaling regulates cell cycle progression in several cell types, primarily by inducing a G1 cell cycle arrest. Tgif1 is a transcriptional corepressor that limits T

Figshare2016-01-19 更新70

Gene expression profiling of stress-induced senescence and paracrine senecence in human hepatocytes

细胞衰老机制

基因表达谱分析

Hepatocytes undergo senescence during development and progression of NAFLD. In order to better understand the phenotype of these senescent cells we generated an in vitro model of stress-induced senesc

NIAID Data Ecosystem60

Ketogenic diet induces p53-dependent cell senescence in multiple organs. Ketogenic diet induces p53-dependent cell senescence in multiple organs

生酮饮食效应

细胞衰老机制

Mice on two different ketogenic diets induce p53 and cellular senescence in multiple organs, including heart and kidney. This is mediated through inactivation of MDM2 by caspase-2 cleavage, leading to

NIAID Data Ecosystem30

Average number of lesions per age group for each pathology group, AOD.

临床病理统计

年龄相关疾病

Average number of lesions per age group for each pathology group, AOD.

NIAID Data Ecosystem60

DataSheet1_Long term high glucose exposure induces premature senescence in retinal endothelial cells.pdf

糖尿病视网膜病变

细胞衰老机制

Purpose: Features of cellular senescence have been described in diabetic retinal vasculature. The aim of this study was to investigate how the high glucose microenvironment impacts on the senescence p

NIAID Data Ecosystem30

Senescent cells and the incidence of age-related diseases

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