Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor DW2
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Crystal structure of PI3K p110gamma catalytical domain in complex with organoruthenium inhibitor DW2 Descriptor: Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, RU-PYRIDOCARBAZOLE-2 Authors: Xie, P, Marmorstein, R. Deposit date: 2008-04-09 Release date: 2008-05-27 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure-based design of an organoruthenium phosphatidyl-inositol-3-kinase inhibitor reveals a switch governing lipid kinase potency and selectivity. Acs Chem.Biol., 3, 2008
创建时间：
2008-04-09
