Electrochemical Generation of Peroxy Radicals and Subsequent Peroxidation of 1,3-Dicarbonyls in an Undivided Cell

The generation of peroxy radicals from hydroperoxides
with subsequent
selective peroxidation of 1,3-dicarbonyls in an undivided electrochemical
cell under constant current conditions is reported. The method provides
a variety of peroxy-containing barbituric acids and 4-hydroxy-2(5H)-furanones with yields of up to 74%. Only the combination
of anodic and cathodic processes provides efficient peroxidation by
generating a set of alkoxy and peroxy radicals. NaNO3 acts
as both an electrolyte and a redox mediator of radical reactions.