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Wound memory of epidermal stem cells [scRNAseq L1-aged]

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NIAID Data Ecosystem2026-03-14 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP361807
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资源简介:
Wound priming in epidermal Lrig1 stem cell progeny leads to a more efficient response to future injuries. To understand if primed progenitors maintain during aging the transcriptional program acquired during wound healing in young age, we performed single cell RNA-Seq of Lrig1 stem cell progeny 40 weeks after injury. Overall design: Single cell RNA-seq transcriptome profiling of epidermal Lrig1 stem cell progenies. After genetical labelling through tamoxifen application, tomato positive epidermal cells were sorted from repaired and age control skin.
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2023-02-03
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