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Trypanothione Reductase from Leismania infantum in complex with TRL190

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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https://pdbj.org/mine/summary/6t97
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Trypanothione Reductase from Leismania infantum in complex with TRL190 Descriptor: 4-[1-[4-[4-(2-phenylethyl)-1,3-thiazol-2-yl]-3-(2-piperidin-4-ylethoxy)phenyl]-1,2,3-triazol-4-yl]butan-1-amine, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... Authors: Carriles, A, Hermoso, J.A. Deposit date: 2019-10-26 Release date: 2020-11-18 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Scaffold hopping identifies new triazole-and triazolium-based inhibitors of Leishmania infantum Trypanothione Reductase with potent and selective antileishmanial activity To Be Published
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2019-10-26
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