S1 Data -

(2A) Scaled sinusodial force across the entire cardiac cycle (750 ms). (2B Time) The time series for the simulation with a step size of 2 ms. (2B Volume) Left ventricular volume throughout the cardiac cycles for the heart failiure case. (2C Time) This is the same as 2B Time series. (2C Pressure) Left ventricular pressure thoughout the cardiac cycles for the heart failure case. (2D Volume) Left Ventricular volume for the converged cardaic cycle of the heart failure case. (2D Pressure) Left Ventriuclar pressure for the converged cardic cycle of the heart failure case. (3A 9 Node Number) Arbitrary indenfication of the epicardial nodes used in the stress analysis. (3A 9 Node Stress) Maximum principal stress values at each of the epicardila nodes nodes. (3A 17 Node Number) Same indentification of the epicardila nodes but for the more refined model. (3A 17 Node Stress) Same stress calculation at the nodes for the more refined model. All 3B parts are the same as their respecitve 4A parts but for the endocardium. (4B noVAD Volume) Left ventricular volume in the converged caridac cycle of the heart failure model. (4B noVAD Pressure) Left ventricular pressure in the converted cycle of the heart failure model. (4B cVAD Volume) Left ventricular volume in the converged caridac cycle of the compression model. (4B cVAD Pressure) Left ventricular pressure in the converted cycle of the compression model. (Fig 5A Force) Values of epicardial applied force normalized to the nominal force. (Fig 5A EF) The left ventricle ejection fraction of the converged cardiac simulation for each applied force. (Fig 5A Pressure) The left ventricle maximum pressure for the converged cardiac simulation for each applied force. (F5B Force) Same as Fig 5A Force. (F5B EDV) The end diastolic volume for the converged cardiac simulation for each applied force. (F5B ESV) The end systolic volume for the converged cardiac simulation for each applied force. (Time No Compression) The time series for the initial heart failure case. (Time Compression) The time series for the nominal compression case. (F6A No Compression Thickening) Thickening percentage of the myocardium in the middle of the compression zone for the HF case. (F6A Compression Thickening)Thickening percentage of the myocardium in the middle of the compression zone for the nominal compression case. (F6B No Compression Hoop Stress) Fiber stress at the transmural depth where fibers are oriented circumferentially in the heart failure case. (F6B Compression Hoop Stress) Fiber stress at the transmural depth where fibers are oriented circumferentially in the nominal compression case. (Fig 6C No Compression Thickening) Myocardial thickening at the apex of the heart in the heart failure case. (Fig 6C Compression Thickening) Myocardial thickening at the apex of the heart in the nominal compression case. (Fig 6D No Compression Thickening) Myocardial thickening at the base of the heart in the heart failure case. (Fig 6D Compression Thickening) Myocardial thickening at the base of the heart in the nominal compression case. (Time) Time series of the converged cardiac cycle for the nominal compression case. (F7A) Maximum strain in the endocardium. P3 –Maximum Principal Strain, E11 –Fiber strain, E22- Cross Fiber Strain, E33 –Transmural Strain. (F7B) Maximum strain in the epicardium. P3 –Maximum Principal Strain, E11 –Fiber Strain, E33 –Transmural Strain. (F7C) Minimum strain in the endocardium. P1 –Minimum Principal Strain, E22 –Cross Fiber Strain, E33 –Transmural Strain. (F7D) Minimum strain in the epicardium. P1 –Minimum Principal Strain, E33 –Transmural Strain, E12 –Fiber-cross fiber shear strain. (Time) Time series of the converged cardiac cycle for the nominal compression case. (F8A) Maximum stress in the endocardium. P3 –Maximum Principal Stress, T11 –Fiber Stress. (F8B) Maximum stress in the epicardium. P3 –Maximum Principal Stress, T11 –Fiber Stress. (F8C) Minimum stress in the endocardium. P1 –Minimum Principal Stress, T33 –Transmural Stress, T12 –Fiber–cross fiber shear stress. (F8D) Minimum stress in the epicardium. (P1) Minimum Principal Stress, T33 –Transmural Stress.
(XLSX)