Supplementary Table 1 from Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States
We used a bioinformatic approach to analyze clonal evolution and genetic architecture in patients with myeloid neoplasia based on SNVs, indels, SVs and CNVs.
Targeted therapy with tyrosine kinase inhibitors (TKI) provides survival benefits to a majority of patients with non-small cell lung cancer (NSCLC). However, resistance to TKI almost always develops a
(Panel A) Amount of SGA in biopsies (dots) and mean SGA over all biopsies at that time point (lines) for individual l (black) and individual f (red). (Panels B and C) Circos plots showing genome-wide
Most human cancers are of monoclonal origin and display many genetic alterations. In an effort to determine whether clonal expansion itself could account for the large number of genetic alterations, w