Histone H3 N-terminus Regulates Higher Order Structure of Yeast Heterochromatin

In budding yeast, telomeres and the mating type (HM) loci are found in a heterochromatin-like silent structure initiated by Rap1 and extended by the interaction of Sir (Silencing Information Regulator) proteins with histones在出芽酵母中，端粒与交配型（HM）位点定位于一类由Rap1启动、并通过Sir（沉默信息调节因子，Silencing Information Regulator）蛋白与组蛋白的相互作用得以延伸的类异染色质沉默结构中。