Gene expression study in CLL of B-cell receptor triggering (mRNA Study)
收藏官方服务：
资源简介：
Gene expression study in CLL of B-cell receptor triggering (mRNA Study)
应用场景：
创建时间：
2014-01-01
相关数据集
Defective Drosha Processing Contributes to Downregulation of MiR-15/-16 in Chronic Lymphocytic Leukemia.. Homo sapiens
MIR15A and MIR16-1, located in chromosomal band 13q14, are tumor suppressor miRNAs often deleted and downregulated in chronic lymphocytic leukemia (CLL). This downregulation is not only due to loss of
NIAID Data Ecosystem70
CD8+ T-cell exhaustion induced by leukemic cells drives progression in Chronic Lymphocytic Leukemia
Mechanisms mediating to disease progression from diagnosis in chronic lymphocytic leukemia (CLL) are not fully elucidated. The acquisition of molecular changes at the time of progression has been obse
NIAID Data Ecosystem40
RBPJ and H3K27ac chromatin IP with sequencing of CLL cells with hyperactivated Notch1 compared to control CLL cells [ChIP-seq]. RBPJ and H3K27ac chromatin IP with sequencing of CLL cells with hyperactivated Notch1 compared to control CLL cells [ChIP-seq]
NOTCH1 gain-of-function mutations are recurrent in B cell chronic lymphocytic leukemia (B-CLL), where they are associated with accelerated disease progression and refractoriness to chemotherapy. The s
NIAID Data Ecosystem30
Aberrant RNA expression and splicing in childhood ETV6/RUNX1 acute lymphoblastic leukemia. Aberrant RNA expression and splicing in childhood ETV6/RUNX1 acute lymphoblastic leukemia
ETV6/RUNX1 E/R -positive acute lymphoblastic leukemia (ALL), as one of the most common childhood malignancies, its pathogenesis and mechanism remain to be elucidated comprehensively. Global gene expre
NIAID Data Ecosystem50
Effects of Blnk reconstitution in BCR-ABL1 driven pre-B cells. Mus musculus
In order to investigate the function of the adapterprotein Blnk in ALL, we isolated bone marrow cells from Blnk KO mice and transformed them with BCR-ABL1. In a second transduction the BCR-ABL1 driven
NIAID Data Ecosystem40
