Impact of test sensitivity on the parameter estimates.

Overview of the impact of imperfect test sensitivity on the estimated susceptibility and infectiousness of older persons (>12 years of age) relative to younger persons (≤12 years of age). The results are obtained using model D in Table 1. For each assumed value of the negative predictive value we give the medians of the parameter estimates of 1000 simulated datasets with 95% bootstrap confidence intervals (between brackets). 1: see equation (2) for the calculation of implied test sensitivity. 2: 95% confidence intervals calculated using the profile likelihood are (0.024–0.43) for relative susceptibility and (0.77–83) for relative infectiousness.