To characterise the human trophoblast cells derived from human ESCs and the effects of ZIKV infection on them, we performed RNA-seq on two sets of samples: 1)human ES cell line HuES8 and the trophobla

NIAID Data Ecosystem30

Human yolk sac-like haematopoiesis generates RUNX1-, GFI1- and/or GFI1B-dependent blood and SOX17-positive endothelium

造血调控

干细胞分化模型

The genetic regulatory network controlling early fate choices during human blood cell development are not well understood. We use human pluripotent stem cell reporter lines to track the development of

NIAID Data Ecosystem20

GAA deficiency in Pompe disease is alleviated by exon inclusion in iPS cell-derived skeletal muscle cells. Homo sapiens

庞贝病基因治疗

干细胞分化模型

While there are many human skeletal muscle disorders, very few therapies have been developed. It has not been possible to generate large amounts of purified skeletal muscle cells from pluripotent stem

NIAID Data Ecosystem30

SARS-CoV-2 infection response in iPSC-derived alveolar epithelial cell type-2. SARS-CoV-2 infection response in iPSC-derived alveolar epithelial cell type-2

病毒感染机制

干细胞分化模型

The coronavirus disease 2019 (COVID-19) pandemic has affected nearly 700 million and claimed more than 6 million lives. However, the large heterogeneity in disease susceptibility and severity of illne

NIAID Data Ecosystem20

Supplementary file 1. Human fetal kidney and hiPSC general information

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