we explore the effects of high concentration of insulin on ovarian grauulosa cells, we then performed gene expression profiling analysis using data obtained from RNA-seq at one time points. KGN cell w

NIAID Data Ecosystem70

White adipose tissue and brain microarray from eIF6 heteroxygotes and wild-type 5 weeks-old mice

胰岛素基因表达

组织特异性基因

White adipose tissue is primary involved in the response to insulin after feeding, while brain is not directly sensitive to insulin levels. We used microarrays to detail the global programme of gene e

NIAID Data Ecosystem50

O-linked β-N-acetylglucosamine (O-GlcNAc) acts as a glucose sensor to epigenetically regulate the insulin gene in pancreatic beta cells. Mus musculus

O-GlcNAc修饰

胰岛素基因表达

We compare global gene expression changes in the Min6 cell line in response to altered glucose flux and pharmacological manipulation of the O-GlcNAc postranslational protein modification. Overall desi

NIAID Data Ecosystem80

high concentration of insulin treated human ovarian granulosa cells(KGN cells)

卵巢研究

胰岛素基因表达

NIAID Data Ecosystem60