RNA-seq of lung myeloid cells from WT and Ptgs2-cKO mice

Alliance of Genome Resources2026-08-01 收录

肺髓系细胞转录组

Ptgs2条件性敲除小鼠

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http://www.informatics.jax.org/gxd/htexp_index/summary?arrayExpressID=E-MTAB-11888 数据链接链接失效反馈

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To investigate the role of the COX-2-dependent lung fibroblast program in reprogramming lung myeloid cells, we generated fibroblast-targeted Ptgs2 conditional knockout mice by crossing Pdgfra-Cre mice with Ptgs2flox/flox mice. Then we isolated two primary types of lung resident DCs-CD103+ conventional DC (cDC1) and CD11b+ conventional DC (cDC2), and lung monocytes from WT and Ptgs2 cKO mice by fluorescence-activated cell sorting and performed RNA sequencing.

RNA-seq of lung myeloid cells from WT and Ptgs2-cKO mice

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