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Synthesis of Polycyclic Heterocycles via a One-Pot Ortho Alkylation/Direct Heteroarylation Sequence

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Synthesis_of_Polycyclic_Heterocycles_via_a_One_Pot_Ortho_Alkylation_Direct_Heteroarylation_Sequence/3371479
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Polycyclic thiophenes and furans were synthesized using a one-pot ortho alkylation/direct heteroarylation reaction sequence. Under the optimized reaction conditions, aryl iodides were coupled with 3-(bromoalkyl)thiophenes or -furans, affording six- and seven-membered annulated ring products via formation of two C−C bonds from two aryl C−H bonds.
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2016-05-12
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