Additional file 3 of Global analysis of suppressor mutations that rescue human genetic defects

Additional file 3: Data S2. Suppression interactions curated from the literature. This file contains the suppression interactions that met our selection criteria (see Methods), along with the corresponding PubMed IDs, details on the query and suppressor genes and mutations, and information on the conditions under which the interactions were identified. It also lists the probability of loss-of-function intolerance and median fitness of gene knockout across cancer cell lines for query and suppressor genes, and contains information on which interactions are annotated to have protein-protein interactions, negative genetic interactions, or positive genetic interactions in the BioGRID, and the mechanistic classes to which the interactions were assigned. Interactions that have been described in more than one paper are listed multiple times.