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SARS-CoV-2 Mpro in complex with compound 18b inhibitor

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Protein Data Bank Japan2026-04-29 更新2026-04-04 收录
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SARS-CoV-2 Mpro in complex with compound 18b inhibitor Descriptor: 3-fluoro-N-[(2S)-1-({(2R)-1-imino-3-[(3R)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-4-methyl-1-oxopentan-2-yl]-4'-methoxy[1,1'-biphenyl]-4-carboxamide, 3C-like proteinase nsp5 Authors: Afsar, M, Bury, P, Olsen, S.K. Deposit date: 2024-04-07 Release date: 2025-04-16 Last modified: 2026-04-29 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Identification and Exploration of a Series of SARS-Cov‐2 M Pro Cyano-Based Inhibitors Revealing Ortho-Substitution Effects within the P3 Biphenyl Group. Acs Med.Chem.Lett., 16, 2025

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2024-04-07
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