JAK1 kinase (JH1 domain) in complex with compound 34
收藏Protein Data Bank Japan2024-11-06 更新2026-03-21 收录
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JAK1 kinase (JH1 domain) in complex with compound 34 Descriptor: 3-(trans-4-{2-[(1R)-1-hydroxyethyl]imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H)-yl}cyclohexyl)propanenitrile, Tyrosine-protein kinase JAK1 Authors: Eigenbrot, C, Steffek, M. Deposit date: 2013-01-22 Release date: 2013-05-22 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Identification of C-2 Hydroxyethyl Imidazopyrrolopyridines as Potent JAK1 Inhibitors with Favorable Physicochemical Properties and High Selectivity over JAK2. J.Med.Chem., 56, 2013
创建时间：
2013-01-22
