five

GSEA of differentially expressed cortical genes in neurocognitive traits.

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https://figshare.com/articles/dataset/_GSEA_of_differentially_expressed_cortical_genes_in_neurocognitive_traits_/348624
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The differentially expressed cortical genes were analysed as gene sets for enrichment of association signal in nine traits from the NCNG GWAS data [37]–[40], using GSEA [32]. Five gene sets were analysed; Gene set 1: combined list of all differentially expressed cortical genes, n = 62, Gene set 2: FMCx genes, n = 29, Gene set 3: TCx genes, n = 22, Gene set 4: OCx genes, n = 11, and Gene set 5: “housekeeping” genes, n = 36 (control gene set, Table S6). The analysis was based on extraction of modified Sidak's minimum P-values [45], as implemented in LDsnpR. FDR q-value<0.1 was set as cut-off value for significant enrichment. For trait abbreviations see Table 4.
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