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Crystal structure of AuroraB/INCENP in complex with BI 811283

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Protein Data Bank Japan2024-11-20 更新2026-03-21 收录
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Crystal structure of AuroraB/INCENP in complex with BI 811283 Descriptor: Aurora kinase B-A, Inner centromere protein A, N-methyl-N-(1-methylpiperidin-4-yl)-4-{[4-({(1R,2S)-2-[(propan-2-yl)carbamoyl]cyclopentyl}amino)-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzamide Authors: Bader, G, Zahn, S.K, Zoephel, A. Deposit date: 2016-05-20 Release date: 2016-08-17 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Pharmacological Profile of BI 847325, an Orally Bioavailable, ATP-Competitive Inhibitor of MEK and Aurora Kinases. Mol.Cancer Ther., 15, 2016

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2016-05-20
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