Precise tuning of gene expression levels in mammalian cells
收藏NIAID Data Ecosystem2026-03-10 收录
官方服务:
资源简介:
Study assays the impact of sequence variation on the repressive strength of synthetic microRNA target sites
应用场景:
创建时间:
2019-01-21
相关数据集
Broad-Spectrum Gene Repression Using Scaffold Engineering of Synthetic sRNAs
Gene expression regulation in broad-spectrum range is critical for constructing cell factories and genetic circuits to balance and control system-wide fluxes. Synthetic small regulatory RNAs (sRNAs) e
NIAID Data Ecosystem40
MicroRNA Target Site Identification by Integrating Sequence and Binding Information. Homo sapiens
High-throughput sequencing has opened numerous possibilities for the identification of regulatory RNA-binding events. Cross-linking and immunoprecipitation of Argonaute protein members can pinpoint mi
NIAID Data Ecosystem30
The increase of miR-378a-3p in keratinocyte associated with pathogenesis of psoriasis. The increase of miR-378a-3p in keratinocyte associated with pathogenesis of psoriasis
We report the high-throughput profiling of human primary keratinocytes transfected with either miR-378 mimic or miR-378 inhibitor at 24 or 48 hours. Our study focused on the dysregulation of microRNAs
NIAID Data Ecosystem20
Simultaneous regulation of many genes using highly non-repetitive extra-long sgRNA arrays
Microbial engineering often requires the regulation of many gene expression levels, for example, to redirect metabolic flows or create complex phenotypes. While CRISPR-based systems enable cross-speci
NIAID Data Ecosystem40
Table_1_Development and Application of Transcription Terminators for Polyhydroxylkanoates Production in Halophilic Halomonas bluephagenesis TD01.xlsx
Halomonas bluephagenesis TD01 is one of the ideal chassis for low-cost industrial production based on “Next Generation Industrial Biotechnology,” yet the limited genetically regulatory parts such as t
NIAID Data Ecosystem20



