X-ray structure of Bace-1 in complex with compound 3.b.10
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X-ray structure of Bace-1 in complex with compound 3.b.10 Descriptor: Beta-secretase 1, N-carbamimidoyl-2-[2-(2-chlorophenyl)-5-[4-(4-ethanoylphenoxy)phenyl]pyrrol-1-yl]ethanamide Authors: Chopra, R, Olland, A. Deposit date: 2007-12-04 Release date: 2008-12-09 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets. Bioorg.Med.Chem.Lett., 18, 2008
创建时间：
2007-12-04
